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KMID : 0032220170290030334
Annals of Dermatology
2017 Volume.29 No. 3 p.334 ~ p.336
Eccrine Squamous Syringometaplasia Associated with Pelubiprofen Therapy
Huh Joon-Won

Jo Min-Gyul
Yoo Ji-Sook
Kim Min-Soo
Choi Kwang-Hyun
Park Hyang-Joon
Jue Mihn-Sook
Abstract
Eccrine squamous syringometaplasia (ESS) is a histologically distinctive skin eruption occurring predominantly in acral or intertriginous areas presenting as erythematous macules, papules or patches. The etiology of ESS remains unclear, but it is usually reported in patients receiving chemotherapy for various malignant neoplasms. To date, only two cases of ESS associated with non-steroidal anti-inflammatory drugs (NSAIDs), which has distinctive clinical features and pathogenesis, have been reported in the literature. Herein, we report a rare and interesting case of ESS associated with pelubiprofen, a recently developed NSAID, which appeared after pelubiprofen therapy and resolved spontaneously after discontinuing the medication.
KEYWORD
Eccrine squamous syringometaplasia, Metaplasia, Pelubiprofen, Phototoxicity
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